New Insights for Understanding Organ Formation

New Insights for Understanding Organ Formation

A group of scientists revealed new theory that was inspired from the wings of fruit fly, which might help in diagnosing and treating human genetic disease.

In a unique discovery, scientists found that the wings of fruit flies might provide links for developing important theories, which could lead to the discovery of cure and diagnosis of various genetic diseases. The findings of the study were published in the journal Current Biology in February 2019.

According to the Rutgers University-New Brunswick study, the theory inspires to influence cells to change its mannerism of expanding and producing new organs. Moreover, the researchers claim that the theory changes the scientific understanding of formation of organs.

The genetic diseases where the organs are malfunctioned due to structural changes including mitral valve prolapse where the valves are unable to function in the right ways and van Maldergem syndrome, where multiple organ fails.

Kenneth D. Irvine, a principal investigator at the Waksman Institute of Microbiology and Distinguished Professor in the Department of Molecular Biology and Biochemistry in the School of Arts and Sciences and senior author of the study, said: “We believe that understanding how wing shape is controlled can also help us understand how the normal shape of many human organs is controlled.”

Through this study, the scientists were able to understand the controlling and designing of organ shape. The researchers used the wing of the common Drosophila fruit fly as a model to analyze their theory. The desired shape of human body is derived due to the specific shapes of the different organs. They observed the division of the cells of the wings of fruit flies and found that tissue-wide stresses are the main factor associated with the division.

We hope this theory will help in opening new avenues in the field of medicine and revolutionizing new treatment for such diseases.

Rina Vidyasagar

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